TURNING NOVEL DISCOVERIES INTO
INNOVATIVE HEALTH CARE SOLUTIONS.
KANE BIOTECH INC. is a biotechnology company engaged in the development of products to prevent and disperse biofilms.
Biofilms are a major cause of a number of serious medical problems including chronic infections and medical device related
infections. They develop on surfaces such as catheters, prosthetic implants, teeth, lungs and the urogenital tract.
Biofilms are pervasive, costly to deal with and approximately 80% of all human bacterial infections involve biofilms.
The healing of chronic wounds alone costs the United States health care system $20 billion per year.
Research Publications - Kane Biotech
- Gawande, et al. (2011). In vitro antibacterial and antibiofilm activity of DispersinB®-Triclosan wound gel against chronic
wound-associated bacteria. The Open Antimicrobial Agents Journal. 3: 12-16.
Link to Publication
- LoVetri, et al. (2010). Biofouling and antifouling of medical devices, p. 105-127. In Chan, J and Wong S (ed), Biofouling: Types,
Impact and Anti-fouling, Nova Science Publisher, NY.
- LoVetri and Madhyastha (2010). Antimicrobial and antibiofilm activity of quorum sensing peptides and peptide analogues against
oral biofilm bacteria. Methods Mol Bio. 618: 383-392.
Link to Publication
- Yakandawala, et al. (2009). Enhanced expression of engineered ACA-less beta-1,6-N-acetylglucosaminidase (dispersin B) in Escherichia coli.
J Ind Microbiol Biotechnol. 36: 1297-1305.
Link to Publication
- Darouiche, et al. (2009). Antimicrobial and antibiofilm efficacy of triclosan and DispersinB® combination.
J Antimicrob Chemother. 64: 88-93.
Link to Publication
- Darouiche, et al. (2008). Efficacy of combination of chlorhexidine and protamine sulfate against device-associated pathogens.
J Antimicrob Chemother. 61: 651-657.
Link to Publication
- Gawande, et al. (2008). Antibiofilm activity of sodium bicarbonate, sodium metaperiodate, and SDS combination against dental unit
waterline-associated bacteria and yeast. J Appl Microbiol. 105: 986-992.
Link to Publication
- Yakandawala, et al. (2008). Metabolic engineering of Escherichia coli to enhance phenylalanine production.
Appl Microbiol Biotechnol. 78: 283-291.
Link to Publication
- Yakandawala, et al. (2007). Effect of ovotransferrin, protamine sulfate and EDTA combination on biofilm formation by catheter-associated bacteria.
J Appl Microbiol. 102: 722-727.
Link to Publication
- Burton, et al. (2007).A microplate spectrofluorometric assay for bacterial biofilms. J Ind Microbiol Biotechnol.
34: 1-4.
Link to Publication
- Burton, et al. (2006) Antibiofilm activity of GlmU enzyme inhibitors against catheter-associated uropathogens.
Antimicrob Agents Chemother. 50: 1835-1840.
Link to Publication
